GFP labeled bacteria inside Aspergillus spore
© N. Keller, Keller Lab

Fungal Pathogenesis

Our survival is inexorably linked to the Kingdom Fungi. Among its many essential roles, fungi contribute to the global recycling of nutrients, the generation of enzymes used in food production, and the production of antimicrobials. Few of the thousands of known fungal species are capable of causing disease, and yet life-threatening infections caused by these pathogens are increasingly prevalent. The ease with which Candida may form biofilms on medical devices contributes to its persistence among nosocomial infections. Pulmonary and systemic infections caused by Aspergillus, Blastomyces, Cryptococcus, and Histoplasma are often misdiagnosed or diagnosed too late to respond effectively to treatment. Resistance to common antifungals is growing. Our fungal pathogenesis faculty seek to alleviate the global burden of fungal infections by understanding and manipulating the dynamic interplay between fungal pathogen and host.


David Andes


(608) 263-1545

5205 Microbial Sciences Building

Gregory Gauthier

Associate Professor of Medicine, CHS

Office: (608) 265-0429, Laboratory: (608) 265-3352

3472 Microbial Sciences Building

Christina Hull

Professor, Biomolecular Chemistry

(608) 265-5441

5204B Biochemical Sciences Building

Nancy Keller

Professor of Medical Microbiology & Immunology and Bacteriology

Office: (608) 262-9795, Laboratory: (608) 262-1958

3476 Microbial Sciences Building

Bruce Klein

Professor of Pediatrics, Medicine, and Medical Microbiology & Immunology

Office: (608) 263-9217, Laboratory: 263-6203

4303 Microbial Sciences Building

Jeniel Nett

Assistant Professor of Medicine and Medical Microbiology & Immunology

Office: (608) 262-7494, Laboratory: (608) 265-0417

5203 Microbial Sciences Building

Jon Woods

Professor of Medical Microbiology & Immunology

Office: (608) 265-6292, Laboratory: 265-6228

4552 Microbial Sciences Building