GFP labeled bacteria inside Aspergillus spore
© N. Keller, Keller Lab

Fungal Pathogenesis

Our survival is inexorably linked to the Kingdom Fungi. Among its many essential roles, fungi contribute to the global recycling of nutrients, the generation of enzymes used in food production, and the production of antimicrobials. Few of the thousands of known fungal species are capable of causing disease, and yet life-threatening infections caused by these pathogens are increasingly prevalent. The ease with which Candida may form biofilms on medical devices contributes to its persistence among nosocomial infections. Pulmonary and systemic infections caused by Aspergillus, Blastomyces, Cryptococcus, and Histoplasma are often misdiagnosed or diagnosed too late to respond effectively to treatment. Resistance to common antifungals is growing. Our fungal pathogenesis faculty seek to alleviate the global burden of fungal infections by understanding and manipulating the dynamic interplay between fungal pathogen and host.

Investigators

David Andes

Position title: Professor

Email: dra@medicine.wisc.edu

Phone: (608) 263-1545

Address:
5205 Microbial Sciences Building

Gregory Gauthier

Position title: Associate Professor of Medicine, CHS

Email: gmgauthier@wisc.edu

Phone: Office: (608) 265-0429, Laboratory: (608) 265-3352

Address:
3472 Microbial Sciences Building

Christina Hull

Position title: Professor, Biomolecular Chemistry

Email: cmhull@wisc.edu

Phone: (608) 265-5441

Address:
5204B Biochemical Sciences Building

Nancy Keller

Position title: Professor of Medical Microbiology & Immunology and Bacteriology

Email: npkeller@wisc.edu

Phone: Office: (608) 262-9795, Laboratory: (608) 262-1958

Address:
3476 Microbial Sciences Building

Bruce Klein

Position title: Professor of Pediatrics, Medicine, and Medical Microbiology & Immunology

Email: bsklein@wisc.edu

Phone: Office: (608) 263-9217, Laboratory: 263-6203

Address:
4303 Microbial Sciences Building

Jeniel Nett

Position title: Associate Professor of Medicine and Medical Microbiology & Immunology

Email: jenett@medicine.wisc.edu

Phone: Office: (608) 262-7494, Laboratory: (608) 265-0417

Address:
5203 Microbial Sciences Building

Jon Woods

Position title: Professor of Medical Microbiology & Immunology

Email: jpwoods@wisc.edu

Phone: Office: (608) 265-6292, Laboratory: 265-6228

Address:
4552 Microbial Sciences Building