Gut Bacterial Molecules Triggering Astrocytes
© V. Vemuganti, Rey Lab

Hawaiian Bobtail Squid
© R. Isenberg, Mandel Lab

An egg infected with bioluminescent influenza virus
© A. Mehle, Mehle Lab

Zebrafish T-cells Highlighted Green Against Red Blood Vessels
© Tanner Robertson, Huttenlocher Lab

Micro CT of Bone Erosion in B. Melitensis Infected Mouse
© Judy Smith, Smith Lab

Fungus Hyphae and Spores in Bat Skin Cells
© Klein Lab

Fixed HMPV infected LLC-Mk2 Cells Stained Blue Against a Viral Fusion Protein, ©Williams Lab

The mission of the Department of Medical Microbiology & Immunology is to provide comprehensive scientific instruction to students, conduct meaningful research, and offer consultation and service in microbiology and immunology as they relate to human health and disease.

Since its founding in 1935, the Department of Medical Microbiology & Immunology has significantly advanced the study of infectious diseases and immunity. Our renowned faculty lead research on bacterial, fungal, protozoan, and viral pathogens such as Toxoplasma gondii, Neisseria gonorrhoeae, Mycobacterium sp., Brucella sp., Listeria, Blastomyces, Aspergillus, Cryptococcus neoformans, Candida, influenza virus, Herpes simplex, enterohemorrhagic E. coli, and uropathogenic Escherichia coli. They also explore immunological topics including regulatory T cell biology, leukocyte migration and vaccine development. Additionally, our labs study the roles of diet, the immune system and the gut-brain-axis in the intestinal microbiome.

Meet Our Researchers

Margaret Alexander, PhD

“Don’t be afraid to ask for help or to fail – one of the best parts about science is that “failures” sometimes lead to the most interesting discoveries!”

Meet Maggie!

John Williams, PhD

“Viruses are like super cool little beasts. Plus, disease always involves the virus and the host – that biological conversation fascinates me.”

Meet John!

Marta Gaglia, PhD

“We are often told that there is one way to do this job and this career – it is not true. If you want to do it, you can do it your own way.”

Meet Marta!

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Recent News

  • Postdoc Zhenyu Zhang Research Published in Nature Communications

    Postdoc Zhenyu Zhang recently published a high-profile paper in Nature Communications (December 2025). The study was a highly collaborative effort involving multiple students and postdocs in the Andrew Mehle lab, along with research partners at …

  • 4 MMI Postdocs Receive WPP Grants

    Supporting the Future of Health Research: Wisconsin Partnership Program Awards a Record 17 Postdoctoral Grants Given the current funding landscape, the Wisconsin Partnership Program (WPP) at the University of Wisconsin School of Medicine and Public …

  • Dr. Mandel Research Featured in ASM Microcosm Journal

    The Mark Mandel Lab is featured in the Fall 2025 issue of Microcosm, the flagship magazine of the American Society for Microbiology (ASM). The article, “Shedding Light on the Vibrio–Squid Symbiosis,” written by Jennifer Tran, PhD, highlights the lab’s …

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