University of Wisconsin - Madison
Biography The major focus of the Smith lab is an intracellular stress response originating from the endoplasmic reticulum (ER) called the “Unfolded Protein Response” or “UPR”. The UPR has been implicated in such diverse processes as viral infection, cancer, neurodegenerative disease, autoimmune diseases, diabetes and cardiovascular disease. We have been most interested in understanding the …
Biography The research in the Vanessa Sperandio lab focuses on how bacterial cells sense mammalian neurotransmitters to gage the physiological and immune state of the host, leading to reprogramming of bacterial transcription towards host and niche adaptation. We have also identified several bacterial adrenergic, endocannabinoid and serotonergic receptors. We have shown that these bacterial neurotransmitter …
Biography Publications Education 1988, Purdue University, W. Lafayette, IN 1995, M.D., Washington U., St Louis, MO 1995, Ph.D., Dr Hultgren (Assembly and Specificity of P pili), Wash U., St Louis, MO 1996-1998, Internal Medicine Residency, CPMC, San Francisco, CA 1998-2001, Infectious Diseases Post-Doctoral Fellow: Stanford University. 1999-2001, Howard Hughes Postdoctoral Fellow, Dr Kirkegaard (In …
Biography