Laura Knoll

B.A. – 1989; Saint Olaf College; Northfield, MN
Ph.D. – 1994; Washington University School of Medicine; St. Louis, MO
Postdoctoral Research- Stanford University; Stanford, CA

Our research centers on studying the host/pathogen interactions of the intracellular parasite Toxoplasma gondii. T. gondii is well known for causing encephalitis in immunocompromised patients and is a member of the coccidian family of parasites that include Plasmodium (causative agent of malaria) and Cryptosporidium (causative agent of diarrhea). My laboratory uses the latest technologies, including next generation sequencing and mass spectrometry, to uncover the parasite and host genes that are necessary for the establishment and maintenance of chronic infection in animals. We then use biochemistry, molecular and cell biology to define the how and why these pathogen and host genes are important.